Prof. Dr. María Vallet Regí, Regí, Universidad Complutense de Madrid - Intelligent Biomaterials Research Group, Academic of the Royal Academy of Engineering and of the Royal National Academy of Pharmacy

When

Location

Maxwell Auditorium & Zoom

Where

ALBA Synchrotron

Website

https://indico.cells.es/event/1604/

Talk open to external members of the ALBA Synchrotron. Registration is required.

Abstract

Our bones can suffer from various types of diseases such as cancer, osteoporosis or infections.

To solve these problems, solutions can be sought with mesoporous silica nanocarriers with pores that can house drugs inside.

Their walls, both inside and outside, can be chemically treated to introduce anti-tumor drugs to destroy cancer cells, biomolecules to fight osteoporosis or antibiotics to treat infections and their surface can be chemically treated to ensure that they do not clump together, are invisible to the immune system and are directed to the right place, that is, they specifically seek out the place where they have to act.

In addition, molecular nanogates can be placed as lids or coatings made of certain polymers to prevent the cargo from escaping prematurely.

Using stimuli such as UV radiation, ultrasound, heat or magnetic signals, they can be made to release their load in the right place and at the right time.

These nanoparticles are true super-agents, versatile, capable of recognizing problems and providing solutions for cancer, osteoporosis and infections.

And they can do this selectively, attacking only the exact areas where the problem exists.